The hormone adiponectin is secreted by fat cells. It aids in reducing tissue inflammatory response to insulin. The pancreas beta cells produce insulin. After blood glucose levels increase adiponectin is released into the blood to help bring them back to normal. By encouraging cells to take in glucose and other nutrients insulin accomplishes this goal. Insulin sensitivity is increased by adiponectin. It promotes the breakdown of fatty acids while reducing the livers ability to produce glucose. Indications for an adiponectin blood test include frequent urination increased thirst fatigue blurry vision rapid weight loss and obesity.