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Unconjugated estriol (uE3) is a type of oestrogen (hormone) that is created by the metabolism of the foetus (unborn child). Babies estriol levels are used to identify chromosomal abnormalities and birth disorders. Estriol which is assessed as unconjugated uE3 is expelled from the placenta an organ that serves as the fetuss protective covering. The main purpose of this test is to identify Down syndrome.
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