Anti-nuclear antibodies, which are frequently associated with autoimmune disorders, are the main kind of anti-SSB antibodies. Systemic lupus erythematosus (SLE), SS/SLE overlap syndrome, subacute cutaneous, primary biliary cirrhosis, etc. are the principal conditions it covers. To ascertain whether SSB antibody is present in the blood or not, an anti-SSB antibody blood test is performed. It aids in evaluating individuals who present with a variety of connective tissue disease signs and symptoms. If the test results are positive, the illness is present. SS-A is mostly made up of cytoplasmic RNA species and protein antigens.