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The protein known as human leukocyte antigen B27 (HLA-B27) is found on your white blood cells surface. HLAs are proteins that are frequently detected on white blood cells. Your immune system uses these antigens to distinguish between healthy body tissue and foreign objects that could spread infection. Although the majority of HLAs shield your body from damage, HLA-B27 is a particular class of protein that impairs the immune system. Your immune system may assault your white blood cells, which are otherwise healthyif they carry the HLA-B27 gene. When this happens, an immune-mediated or autoimmune diseasesuch as juvenile rheumatoid arthritis or ankylosing spondylitismay develop.
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