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This test is intended to be used as an aid for the diagnosis of acute or recent leptospirosis. The clinical features of leptospirosis can vary, ranging from a mild, flu-like illness (eg, headache, malaise, fever, fatigue) to a a severe disease with liver and kidney involvement. IgM antibodies to Leptospira species suggest recent infection and is detectable within 1-2 weeks after the onset of the illness and peaks at 2-4 weeks.
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