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Multiple myeloma, renal tubular abnormalities, as well as other immunological diseases, are all diagnosed with the beta-2 microglobulin test. This test measures the amounts of beta-2 microglobulin in serum (blood) and urine. MHC-1, a protein complex made up of beta-2 microglobulin, a cell membrane protein, is (HLA in humans). Both Beta-2 microglobulin levels and MHC proteins rise during an immunological response. In light of this, this test serves as a tumour marker for several hematologic malignancies.
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