A blood test known as the LE Cells test is used to locate lupus cells in an individual. Previously this test was used to diagnose Systematic Lupus Erythematosus; however the Anti-nuclear Antibody Blood Test which is regarded as the gold standard has since taken its place. Antibodies which are defensive proteins that weaken a variety of tissues are what cause it. Additionally it has an impact on the kidneys brain heart lungs skin and joints. Fever rashes joint pains exhaustion or light sensitivity are indicators that LE cells testing is necessary.