Gamma-glutamyl transferase (GGT) is an enzyme that is found in many organs throughout the body with the highest concentrations found in the liver. GGT is elevated in the blood in most diseases that cause damage to the liver or bile ducts. This test measures the level of GGT in a blood sample. Normally GGT is present in low levels but when the liver is injured the GGT level can rise. GGT is usually the first liver enzyme to rise in the blood when any of the bile ducts that carry bile from the liver to the intestines become obstructed for example by tumors or stones. This makes it the most sensitive liver enzyme test for detecting bile duct problems