A blood test known as the LE Cells test is used to locate lupus cells in an individual. Previously, this test was used to diagnose Systematic Lupus Erythematosus; however, the Anti-nuclear Antibody Blood Test, which is regarded as the gold standard, has since taken its place. Antibodies, which are defensive proteins that weaken a variety of tissues, are what cause it. Additionally, it has an impact on the kidneys, brain, heart, lungs, skin, and joints. Fever, rashes, joint pains, exhaustion, or light sensitivity are indicators that LE cells testing is necessary. Even though there are other ways to test LE cells, the most secure procedure is to take a blood sample.