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TNF-alpha is an inflammatory cytokine that cells produce during acute inflammation in a variety of medical disorders. If you have a fever, low blood pressure, muscle aches, loss of appetite, redness, or swelling; you might need this test. The test is used to identify a number of inflammatory disorders, including ankylosing spondylitis, psoriasis and arthritis. Patients with cancer and suspected gram-negative infections can also benefit from the test.
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