Insulin resistance can be detected with the HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) test. When cells become resistant to the effects of insulin, your body must create more insulin to keep blood sugar levels under control. Based on your fasting blood sugar and insulin levels, this test determines how much insulin your pancreas needs to generate to maintain stable blood sugar levels. Your insulin resistance is more serious the higher your score. The risk of acquiring diabetes and the effectiveness of therapy are both evaluated by this test.