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The diagnosis of pernicious anemia and the etiology of vitamin B12 deficiency can both be confirmed with an intrinsic factor antibody (IF antibody) test. If other laboratory tests, including a vitamin B12 test, a methylmalonic acid test, and a complete blood count (CBC), have determined that a person has a vitamin B12 deficiency and associated anemia and/or neuropathy, which is numbness, tingling, pain, or weakness in an affected area, antibody testing is typically used in follow-up.
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