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CMV IgG and IgM antibodies are produced in response to a CMV infection. IgG antibodies are the most common type of antibodies produced in response to a CMV infection, whereas IgM antibodies are the first type of antibodies to appear in the bloodstream during an active or recent CMV infection. A positive CMV IgM and negative IgG means you may have very recently been infected4. The presence of IgG antibody generally indicates past exposure and immunity, while the presence of IgM antibody indicates recent infection
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