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To detect and identify Pemphigus, the Desmoglein I antibody test (DSG I antibody test) is used. Desmoglein, a protein that functions as a kind of glue that binds the epidermal cells or skin cells together, is the target of antibodies that are produced in the autoimmune disease pemphigus. Desmoglein is destroyed by antibodies that are directed towards oneself. The doctor orders this test to determine what is causing sores and blisters on the skin's surface. In evaluating painful blisters that begin close to the lips, it is also beneficial.
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