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PAPP-A (pregnancy-associated plasma protein-A) tests keep track of the amount of PAPP-A that the placenta releases while a woman is pregnant. A low level of PAPP-A could be a sign that the foetus is at risk for genetic abnormalities. During the first and second trimesters of pregnancy this test aids in determining the likelihood that the growing infant may have aneuploidies such as trisomy 21 and down syndrome
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