Several processes in growth, development, and general health require proteins. Albumin and globulin make up the two main protein subgroups in blood. Nearly 60% of the proteins in blood are made up of albumin. It is largely important for tissue metabolism and is produced by the liver. Energy is used during metabolism. The remaining 40% of blood's proteins are found in globulin. Numerous enzymes, antibodies, and hormones are produced by globulins. As seen, the ratio of albumin to globulin will typically be just over 1, as albumin is typically present in higher amounts than globulin. The protein count in blood can be checked using this as a useful reference to identify any anomalies.