Detection of Mycobacterium tuberculosis may take up to three to eight weeks by the traditional, culture method. As an alternative, The Urine PCR (a DNA amplification test) has emerged as a rapid and reliable diagnostic tool and a method to detect the DNA of Mycobacterium tuberculosis from a urine sample, with many results available the same day.Therefore, A PCR test ensures a rapid detection of the bacteria and is helpful in initiating treatment in time.The test may be prescribed if someone is presented with the symptoms suggestive of tuberculosis. Such symptoms include fever, persistent cough with phlegm having bloody streaks, unexplained weight loss, loss of appetite, fatigue, weakness, chest pain and night sweat. The test may be ordered if rapid detection of Mycobacterium tuberculosis is required.