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A mutation is a change in a gene's structure that can result in a number of problems. The JAK2 V617F gene mutation, which is frequently linked to myeloproliferative illnesses such polycythemia vera (PV), essential thrombocythemia (ET), and myeloproliferative malignancies, is detected by this test. Blood malignancies of the myeloproliferative subtype start in the bone marrow. DNA that was isolated from the blood sample is used for the test.
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